Biophysics of DNA-Protein Interactions: From Single by Mark C. Williams,III, L. James Maher PDF

By Mark C. Williams,III, L. James Maher

Depite the swift growth of the sphere of biophysics, there are only a few books that comprehensively deal with particular subject matters during this sector. lately, the sector of unmarried molecule biophysics has constructed in a short time, and some books in particular treating unmarried molecule equipment are commencing to seem. in spite of the fact that, the promise of unmarried molecule biophysics is to give a contribution to the certainty of particular fields of biology utilizing new equipment. This publication may concentrate on the categorical subject of the biophysics of DNA-protein interactions, and would come with using new methods, together with either bulk equipment in addition to unmarried molecule equipment. this may make the publication appealing to an individual operating within the basic region of DNA-protein interactions, that is in fact a wider industry than simply unmarried molecule biophysicists or perhaps biophysicists.


The topic of the booklet often is the biophysics of DNA-protein interactions, and should contain new tools and effects that describe the actual mechanism through which proteins engage with DNA. for instance, there was a lot contemporary paintings at the mechanism wherein proteins look for particular binding websites on DNA. a couple of chapters should be dedicated to experiments and thought that make clear this significant challenge. we'll additionally conceal proteins that regulate DNA houses to facilitate interactions very important for transcription or replication. one other element of the booklet will conceal the biophysical mechanism in which motor proteins have interaction with DNA. eventually, we'll hide better protein-DNA complexes, comparable to replication forks, recombination complexes, DNA fix interactions, and their chromatin context.

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Biophysics of DNA-Protein Interactions: From Single Molecules to Biological Systems (Biological and Medical Physics, Biomedical Engineering) by Mark C. Williams,III, L. James Maher


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